“The U.S. Food and Drug Administration on Thursday recommended COVID-19 vaccine manufacturers change the design of their booster shots beginning this fall to include components tailored to combat the currently dominant Omicron BA.4 and BA.5 subvariants of the coronavirus.”
SOURCE:
US FDA wants COVID boosters targeting Omicron BA.4, BA.5 subvariants
These idiots are coming with this new plan after we have shown them that key is”
1)you must reduce the infectious pressure; there is too much virus remaining in the environment after each wave and it is not coming down to baseline, thus we are not cutting the chain of transmission so will never get to herd immunity; we need antiviral chemoprophylaxis for the society, antivirals we always had and were urging
2)are these idiots at FDA etc. not grasping that by the time this retooled vaccine is rolled out, that there will be new dominant variants/clades and the vaccine will be akin to how it is now, ‘worthless’? Presently we are using vaccines based on the legacy Wuhan strain when we had Delta and Omicron circulating and Wuhan was long gone.
These bitches at NIH like Collins and Fauci at NIAID et al. had you vaccinating with a vaccine that could have never ever worked and they knew it. The vaccinal antibodies could not hit the omicron variants and they knew. This is why there was immune escape and vaccinated were getting infected. Moreover Yahi et al. has shown us the vaccinal antibodies are so worthless, they are dangerous, for they bind to the target spike antigen (receptor binding domain epitopes on the spike or N terminal domain epitopes) yet do not sterilize (neutralize) the virus and prevent infection. In fact, the binding of non-neutralizing vaccinal antibodies enhances and facilitates infection in the vaccinee, called antibody dependent enhancement of infection (ADEI). There is also pressing original antigenic sin (OAS) where initial exposure imprinting, priming prejudices the subsequent exposure to the initial exposure antibody response, and thus Wuhan antibodies are recalled.
They have greatly disregarded and underestimated the evolutionary capacity of the virus to evolve and adapt to the pressure around it. They deal with this as if based only on the virus’s intrinsic properties and not the environmental pressure and the virus-host immune system interactions. A complex interplay. It is the non-neutralizing antibodies that is the key in this insanity, causing the damage.
