“The work that had been done over the years on formulations, RNA modifications and other techniques was paying off just in time for the current pandemic. mRNA vaccination was in exactly the right stage for things to take off with a good expectation of success.”
It helps to know how we got here, and the following timeline traces the creation of the DARPA-Big Pharma package of solutions for SARS-CoV-2 and illustrates just how ready they all were. Every outbreak furthered the development of genetic vaccines. Cases were counted according to tests, then compared to deaths ‘associated with’ the virus in question. Every outbreak featured a virus with a cleavage site, and they can all be stabilized with the NIH’s pre-fusion design, just like the rona.
The ronascam solutions were vastly enabled by, i) Baric, Shi and Daszak making bat coronaviruses able to infect humans, and suggesting targets for vaccines, ii) Graham at the VRC developing vaccines, iii) Mclellan, Ward, and others from Dartmouth College and Scripps perfecting the pre-fusion technique, and iv) working closely with Moderna and Curevac to turn it all into mRNA. Plus, of course, a huge amount of money.
All they needed was a pandemic and nothing could have been better than SARS-CoV-2. It’s a virus with an unexplained furin cleavage site that appears to have been made in a lab. It spreads far and wide but without causing chaos. SARS-CoV-2 gets genetic vaccines in by the back door and it kick-starts the Reset. Presumably we’re just lab rats until this phase is over because Gates and Schwab have promised us much worse is to come (apparently a cyber-attack), by which point things’ll be so chaotic, clinical trials will no longer be possible and vax-passports will be mandatory.
- Curevac is founded (mRNA potions).
- Methods for producing recombinant coronavirus – patent filed by Baric et al., at the University of North Carolina, Chapel Hill. The coronavirus particles “can be readily targeted to other mucosal surfaces mammalian species such as swine by simple replacements in the S glycoprotein gene, which has been shown to determine tissue and species tropism”, i.e. the particles can be made to infect certain body tissues (e.g. lungs), and even different species of animal, by altering the spike protein (e.g. mutating amino acid residues). The patent acknowledges the danger inherent in this kind of biological material by noting, “the possibility of RNA recombination between the replicon RNA and wild-type virus cannot be eliminated and remains an important issue requiring additional analysis.”
- Operation Dark Winter – simulation of anthrax and smallpox attacks, followed by real anthrax attacks.
- SARS outbreak begins in China. SARS stands for ‘Severe Acute Respiratory Syndrome’ and is said to be a new atypical pneumonia. The virus is said to have jumped from bats to civet cats, and then to humans.
- The WHO announces the end of the SARS outbreak (there were 8,098 cases and 744 deaths).
- Baric works with researchers from U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, to make clones of SARS (Urbani strain). The clones are also infectious, which, they claim, “provides a template for manipulation of the viral genome, allowing for the rapid and rational development and testing of candidate vaccines and therapeutics…”
- Since 2003, “there have been six documented SARS disease outbreaks originating from research laboratories, including four in China. These outbreaks caused 13 individual infections and one death.”
- Second Lab Accident Fuels Fears About SARS
- Researchers begin collecting bat coronaviruses to try and find ones like SARS hoping to prove it came from bats.
- Shi and Daszak publish ‘Bats are natural reservoirs of SARS-like coronaviruses’.
- Atlantic Storm, another simulation of a smallpox attack.
- Kariko et al publish the ‘landmark’ paper suggesting mRNA can be made to work if artificial or modified versions are used (such as methylated pseudouridine). She then got funding from the NIH, and the University of Pennsylvania filed patents which were eventually assigned to the NIH.
- The WHO rewrites its International Health Regulations which are binding on all member states (i.e. most of the world!). A Public Health Emergency of International Concern (PHEIC) is defined as an extraordinary event which “constitute[s] a public health risk to other States through international spread of disease and…potentially require[s] a coordinated international response”. Subsequently, a total of six PHEICs were declared: H1N1 (2009), Polio (2014), Ebola (2014 and 2019), Zika (2016) and SARS-CoV-2 (2020).
- The NIH and the EU form the AIDS-CoVAC consortium to create “a novel coronavirus-based HIV vaccine vector that is optimized for host entry”.
- The NIH begin trial of a DNA vaccine for H5N1 (bird flu)
- Baric et al. make some chimeric, synthetic bat-origin SARS coronaviruses that can infect human cells.
- Japanese researchers create a SARS spike protein with a furin cleavage site (like the one that’s strangely appeared in SARS-CoV-2).
- BioNTech is founded (teamed with Pfizer in 2020)
- The WHO changes the definition of a flu pandemic so that deaths and illness are no longer relevant, then declare a swine flu pandemic which lasts until 2010, and is later found to be fake.
- The VRC begin a Phase 1 trial of a DNA-based vaccine for swine flu, just two months after the WHO declare a pandemic. The vaccine was manufactured at the VRC/NIAID/Vaccine Pilot Plant using E. coli bacteria.
- The NIH begins a phase 2 trial of a DNA-based HIV vaccine, called HVTN; (trial is halted in 2013).
- The U.S. Agency for International Development (USAID) initiates a new global emerging pandemic threat program called PREDICT, and it’s based on EcoHealth Alliance’s ‘hotspots’ map.
- Bill and Melinda Gates pledge $10 Billion for ‘the Decade of Vaccines’ (2010-2020)
- Zheng Li Shi et al. publish, Angiotensin-converting enzyme 2 (ACE2) proteins of different bat species confer variable susceptibility to SARS-CoV entry
- Moderna is founded – but by who? In September, Derrick Rossi’s paper on mRNA is published and the media narrative, promoted by Rossi, is that this is the research that inspired him to set up Moderna with Tim Springer and Kenneth Chien from Harvard and Robert Langer from MIT. However, he was no expert on mRNA, he appears not to have continued researching mRNA (Rossi’s papers are here), and he’s now disappeared from the founding story altogether. According to Wikipedia, Moderna was founded by Flagship Pioneering/Noubar Afeyan, Springer, Chien and Langer.
- Moderna files patent (‘Engineered nucleic acids and methods of use thereof’)